Hiroshi Maruta, PAK Research Center, Melbourne
Australia.
During last 6 months, COVID-19 killed more than
600,000 people world-wide, mainly due to the mishandling by both Chinese
government and WHO. However, this COVID-19 based loss of lives is less than 1 /1000
% of the total world population (70 billions). In my opinion, the most serious
problem in this planet is not “pandemic” bacterial or viral infection any more,
but “over-population” of human beings in this “limited” space. Since the Chinese
communist government (CCG) declared the impressive “one child per family”
policy in 1949, the population in CCG ironically increased from 6 billions to
14 billions during 7 decades. Obviously this policy failed. Similarly the Indian
population in the subcontinent increased from < 5 billions to 14 billions. Why
did both over-populated Asian countries fail the crucial “birth-control”?
In the past (before WWII), hygienic control was
very poor, and the fatality of baby or young child was very high. That is why people have to produce more than 1
child per family. However, due to a great improvement of hygienic and other
medical conditions, general fatality becomes quite low, perhaps except for war
zones, and therefore the reasonable “birth control” became necessary for
blocking the over-population of human beings. However, very unfortunately, (post
WWII) WHO has paid their attention, only little if any, to the birth control. That
is why we are now severely suffering from a series of “global warming” effects,
such as bush fires ( in California and Southern Ausralia) and increase in sea
levels world-wide, which are caused by release of too much CO2 gas into atomosphere (produced from
burning coal , oil and propan gas for cars and airplanes etc).
Usually CO2 is consumed by plants,
but too much logging activity for housing and farming, the native forests have
been drastically shrinked. Thus, it is very clear that if WHO is intended to
maintain or improve our health conditions, that is QOL (quality of life) of
both human beings and other animals on this planet, they have to control “effectively”
the birth of human beings simulatanously, before promoting
the “old-fashioned” (time-consuming) anti-viral vaccine development/ production.
In my expert opinion, a series of PAK1-blockers, readily available in the
market, such as propolis and ivermectin will take care of these (PAK1-dependent)
viral pandemics:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166201/
Alternatively, we could send 28 billions of
people in both Chinese and Indian territories by “jumbo” rockets with a plenty
of water and oxygen (or combination of CO2 and plant seeds) to Moon or
Mars. Through “photosynthesis”, they can produce a plenty of oxygen from plants
for both people and other animals. Lands in both Moon and Mars are currently free,
and they can enjoy an “unlimited” sex life (without any birth-control!). Then the
rest of us (60% of current population) could enjoy the better QOL (quality of
life) on this planet.
Well, domestic migration
to either Moon or Mars will probably take decades or a century. Until then, what
shall we do for saving this planet from either over-population or global
warming caused by too much emission of CO2? Back in 1973, I left Japan by a giant
contenna liner (tanker), instead of airplane to reach the US. It took non-stop 9
days from Yokohama to Seattle. On this ship, only 13 passengers were allowed to
get on board. In the US, and in any other places, I have never driven a car. I always
use public trans-portation or walk on my own feet throughout my entire life. It
sounds very frugal, but is “accomplishable”. After COVID-19 pandemic, more than
90% airplanes world–wide remain landed. Many pilots look for their new job in
airforces, because nobody knows when or whether these airplanes fly again. Consequently
world-wide tourism was turnished. If everybody stop driving their own cars and
taking airplanes, a huge amount of CO2 emission would be reduced. As
soon as COVID-19 “lockdown” started, anyone could notice that air quality is
remarkably improved all of a sudden even in Beijing. That should be what we are
supposed to do for the first place.
Furthermore keep briskly walking or
biking will save at least 25% of world population from the “obesity” as well,
and people with obesity turn out to be the most mortal with COVID-19!
Just like cancers, obesity is among PAK1-dependent diseases, and exercise suppresses PAK1, the major “pathogenic” kinase.
Reduced fertility and extended lifespan of
PAK1-deficient animals
In theory, the best approach to “birth control”
of human beings (and any other animals) is “genetic deletion” of PAK1 gene. I will tell you the “scientific” reason: For an instance, deletion of PAK1 gene from
C. elegans, reduces their fertility to 1/7, and extends their healthy lifespan by
60%. In any animals the fertility and longevity trade off: in short, sex kills! However, at least in the case of human
beings, we are not allowed as yet to perform any genetic manipulation (during
IVF), except for the very special case (s) where without it, the given IVF baby
is expected to die shortly after its birth.
However, there are a few alternative (non-genetic)
approaches for the birth control: (i) usage
of condom, (ii) taking a “birth-control pill”, (iii) sterilizing male or female
genitals after the birth of the first child per family, and (iv) taking
PAK1-blockers such as propolis, vitamin D3, ivermectin, melatonin etc,
which reduce our fertility to 1/7 (but promote our longevity). In my opinion, WHO and world-leaders should
promote seriously these birth controls world-wide to save our planet from both “over-population”
and “global warming”.
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