2020年4月18日土曜日

“Propolis Therapy of COVID-19”:
Letter from a Dutch chemist


Dear (Propolis) Scientists:
I want to inform you that in the Netherlands, one month ago we started an initiative with more than hundred beekeepers to collect an amount of propolis that is enough to investigate the treatment of Corona patients with propolis, an ethanol  extract of bee-hives. 
Dr. Maruta in Melbourne has recently suggested that propolis, which blocks the major "pathogenic" kinase (PAK1),  has a high potential in case of Corona#. So we thought to give it a try.
Early experiences in the Netherlands: Especially from a district that is heavily infected, first signs from users during the past month are positive: the symptoms are less severe and patients can recover at home without hospital care.
Very sick adults were first treated with more than 1 gram propolis/day on a basis of propolis powder in capsules or tablets.
We know that the ethanol extraction increases the effectiveness of the propolis, so the dosage of propolis tincture can be lower.
For providing  the propolis in an easy way to dose, we mixed it with good honey (cold processed) from biological safe grounds (free of pesticides/herbicides etc.).
This mixture contained 1% to 5% pure propolis, based on ethanol extract with circa 30 to 40 w% pure propolis.

On this short notice we see that for moderate symptoms the 1% propolis-honey mixture,  2 or 3 times a day 0.5 gram honey is enough. Severe symptoms take higher doses.
We are in preparation of a large scale clinical trial, and would appreciate your own experiences in this matter.
If you know any colleagues who investigate propolis on COVID-19 patients, please let us share our results and knowledge.
We also spread out a guide for people to make propolis-honey by themselves in the easiest way, to reduce the number of people that need hospital care:
Thank you all for your research on propolis, keep up the good work!

Kind regards,

Annette van der Knaap
Chemist, research on propolis quality in the Netherlands and the rest of world.
+31 416 391402
a.van.der.knaap@planet.nl ________________________________________________________________________
#
For detail, see Hiroshi Maruta and Hong He (2020)
PAK1-blockers: Potential Therapeutics against COVID-19.

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